Standard

Suffering from nerves

ACP2 · rs12787112

Where this position leads

Condition: Irritable Mood

rs12787112 Condition: Irritable Mood Irritable Mood Condition rs12787112 rs12787112 ACP2

What the study found

Who was studied 369,499 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 8.13 z score higher; p = 4 × 10−16.

How common The A allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — in an intron of AGBL2.

What each result means

A/A Two copies of the version the research linked to Suffering from nerves. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Suffering from nerves. That is a smaller link than two copies.
G/G No copy of the version the research linked to Suffering from nerves. This is the starting point the study compared everyone against.
Source

Questions about rs12787112

What is rs12787112?

rs12787112 is a single position in the genome, in or near the ACP2 gene. Published research associates it with suffering from nerves. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12787112 linked to?

On MyGeneLog this position is linked to Irritable Mood. The research behind each link, and its sources, are set out on that condition page.

Does having rs12787112 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12787112 come from?

GWAS Catalog, Nature communications 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Suffering from nerves (rs12787112). MyGeneLog™. https://www.mygenelog.com/variants/rs12787112

← See all variants