Standard
Eosinophil count
IKZF2 · rs12619285
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Eosinophil count — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Eosinophil count.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Eosinophil count compared to the general population.
Source
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
Gudbjartsson DF,
Bjornsdottir US,
Halapi E,
Helgadottir A,
Sulem P,
Jonsdottir GM,
Thorleifsson G,
Helgadottir H,
Steinthorsdottir V,
Stefansson H,
Williams C,
Hui J
and 61 more — show all
Beilby J,
Warrington NM,
James A,
Palmer LJ,
Koppelman GH,
Heinzmann A,
Krueger M,
Boezen HM,
Wheatley A,
Altmuller J,
Shin HD,
Uh ST,
Cheong HS,
Jonsdottir B,
Gislason D,
Park CS,
Rasmussen LM,
Porsbjerg C,
Hansen JW,
Backer V,
Werge T,
Janson C,
Jönsson UB,
Ng MC,
Chan J,
So WY,
Ma R,
Shah SH,
Granger CB,
Quyyumi AA,
Levey AI,
Vaccarino V,
Reilly MP,
Rader DJ,
Williams MJ,
van Rij AM,
Jones GT,
Trabetti E,
Malerba G,
Pignatti PF,
Boner A,
Pescollderungg L,
Girelli D,
Olivieri O,
Martinelli N,
Ludviksson BR,
Ludviksdottir D,
Eyjolfsson GI,
Arnar D,
Thorgeirsson G,
Deichmann K,
Thompson PJ,
Wjst M,
Hall IP,
Postma DS,
Gislason T,
Gulcher J,
Kong A,
Jonsdottir I,
Thorsteinsdottir U,
Stefansson K
Nature genetics · 2009 · PMID 19198610
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs12619285
What is rs12619285?
rs12619285 is a single position in the genome, in or near the IKZF2 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs12619285?
Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs12619285 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs12619285 come from?
GWAS Catalog, Nat Genet 2009, PMID:19198610. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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