Standard

Eosinophil count

IKZF2 · rs12619285

Where this position leads

Condition: Blood Cell Counts

rs12619285 Condition: Blood Cell Counts Blood Cell Counts Condition rs12619285 rs12619285 IKZF2

What the study found

Who was studied 9,392 European ancestry individuals; replicated in 12,118 European ancestry individuals, 5,212 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 6.3 % standard unit higher (95% confidence interval 4.3-8.3); p = 5 × 10−10.

How common The G allele had a frequency of about 74% in the people studied.

Where it sits Chromosome 2, band 2q34 — in an intron of LOC102725082.

What each result means

A/A No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs12619285

What is rs12619285?

rs12619285 is a single position in the genome, in or near the IKZF2 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs12619285 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs12619285?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs12619285 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12619285 come from?

GWAS Catalog, Nat Genet 2009, PMID:19198610. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eosinophil count (rs12619285). MyGeneLog™. https://www.mygenelog.com/variants/rs12619285

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