Standard

Bone mineral density

MEF2C · rs11951031

Where this position leads

Condition: Heel Bone Mineral Density

rs11951031 Condition: Heel Bone Mineral Density Heel Bone Mineral Density Condition rs11951031 rs11951031 MEF2C

What the study found

Who was studied 5,866 European ancestry individuals; replicated in 715 Mexican American individuals.

The effect Each copy of the T allele shifted the measure 0.2 lower (95% confidence interval 0.12-0.28); p = 9 × 10−9.

How common The T allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 5, band 5q14.3 — in an intron of MEF2C.

What each result means

C/C No copy of the version the research linked to Bone mineral density. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Bone mineral density. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Bone mineral density. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11951031

What is rs11951031?

rs11951031 is a single position in the genome, in or near the MEF2C gene. Published research associates it with bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11951031 linked to?

On MyGeneLog this position is linked to Heel Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs11951031?

Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11951031 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11951031 come from?

GWAS Catalog, J Med Genet 2013, PMID:23572186. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Bone mineral density (rs11951031). MyGeneLog™. https://www.mygenelog.com/variants/rs11951031

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