Body mass index and fasting glucose (pairwise)
ADCY5 · rs11708067
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 380,336 European ancestry individuals, 16,962 East Asian, South Asian, Hispanic and African American ancestry individuals.
The effect The reported allele is G; the catalogue records no effect size ; p = 4 × 10−9.
How common The G allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 3, band 3q21.1 — in an intron of ADCY5.
What each result means
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
In the news
2026-05-22 · Sinnott-Armstrong N, et al., Nature Communications 2026, PMID:42173832
Genetic variants affect diurnal glucose levels throughout the day
Circadian rhythms regulate glucose metabolism as well as sleep, but which genetic variants govern the timing of glucose had not been examined. Using the time of day each blood sample was taken, this study of about 420,000 UK Biobank participants — replicated in the Estonian Biobank, FinnGen, the VA Million Veteran Program and the MGB Biobank — shows that glucose levels are under diurnal genetic control. The two robust time-dependent signals are at MTNR1B, the melatonin receptor (rs10830963), and at CRY2, a core circadian clock gene (rs12419690). Sleep modulated glucose levels, the variants acted independently of sleep, they independently changed the risk of type 2 diabetes, and sleep medications including melatonin were associated with type 2 diabetes. Those two headline positions are not on this site yet; 21 other positions from the study are, among them rs560887 (G6PC2), rs34872471 (TCF7L2), rs3802177 (SLC30A8) and rs11708067 (ADCY5). PMID:42173832.
From our blog
Questions about rs11708067
What is rs11708067?
rs11708067 is a single position in the genome, in or near the ADCY5 gene. Published research associates it with body mass index and fasting glucose (pairwise). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs11708067?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (15 papers), heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs11708067 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11708067 come from?
GWAS Catalog, Nat Metab 2021, PMID:33619380. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index and fasting glucose (pairwise) (rs11708067). MyGeneLog™. https://www.mygenelog.com/variants/rs11708067