Sensitive

Squamous cell carcinoma

LPP · rs11707807

Where this position leads

Condition: Squamous Cell Carcinoma

rs11707807 Condition: Squamous Cell Carcinoma Squamous Cell Carcinoma Condition rs11707807 rs11707807 LPP

What the study found

Who was studied 9,674 European ancestry cases, 625,657 European ancestry controls.

The effect Each copy of the G allele carried 1.10 times the odds of Squamous cell carcinoma (95% confidence interval 1.06-1.14); p = 3 × 10−11.

How common The G allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 3, band 3q28 — in an intron of LPP.

What each result means

A/A No copy of the version the research linked to Squamous cell carcinoma. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Squamous cell carcinoma. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Squamous cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11707807

What is rs11707807?

rs11707807 is a single position in the genome, in or near the LPP gene. Published research associates it with squamous cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11707807 linked to?

On MyGeneLog this position is linked to Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs11707807 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11707807 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:31174203. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Squamous cell carcinoma (rs11707807). MyGeneLog™. https://www.mygenelog.com/variants/rs11707807

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