C/CPublished research associates this genotype with typical/baseline likelihood of Systemic lupus erythematosus — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systemic lupus erythematosus.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systemic lupus erythematosus compared to the general population.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs11684176
What is rs11684176?
rs11684176 is a single position in the genome, in or near the PLCL1 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11684176 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs11684176?
Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs11684176 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11684176 come from?
GWAS Catalog, Ann Rheum Dis 2020, PMID:33272962. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.