A/APublished research associates this genotype with typical/baseline likelihood of Disease progression in age-related macular degeneration — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Disease progression in age-related macular degeneration.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Disease progression in age-related macular degeneration compared to the general population.
rs116503776 is a single position in the genome, in or near the C2 gene. Published research associates it with disease progression in age-related macular degeneration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs116503776 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs116503776 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs116503776 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:29346644. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.