0 18132327Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 43,559 European ancestry cases, 384,389 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.0679 higher (95% confidence interval 0.053-0.083); p = 1 × 10−22.
How common The A allele had a frequency of about 54% in the people studied.
Where it sits Chromosome 15, band 15q22.33 — in an intron of SMAD3.
What each result means
A/ATwo copies of the version the research linked to Spinal stenosis (PheCode 720). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Spinal stenosis (PheCode 720). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Spinal stenosis (PheCode 720). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs11635145
What is rs11635145?
rs11635145 is a single position in the genome, in or near the SMAD3 gene. Published research associates it with spinal stenosis (phecode 720). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11635145 linked to?
On MyGeneLog this position is linked to Spinal Stenosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs11635145 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11635145 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 18132327Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others7Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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