0 261185227Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot5Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others7Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 115,486 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.094 lower (95% confidence interval 0.06-0.128); p = 4 × 10−8.
How common The C allele had a frequency of about 80% in the people studied.
Where it sits Chromosome 10, band 10q25.3 — in an intron of TCF7L2.
What each result means
C/CTwo copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
rs11594566 is a single position in the genome, in or near the TCF7L2 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11594566 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs11594566 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11594566 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:29617998. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 261185227Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI8Microsoft · Copilot5Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others7Total26Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.