2 5432818222125Reads by AI crawlersClaude3ChatGPT2Google · Gemini8Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others25Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
A/ATwo copies of the associated allele. Still a small shift, and still not a finding an individual can act on. The reason to record it is what it points at biologically, not what it predicts.
T/AOne copy of the associated allele. The allele is common everywhere and much commoner in African populations (about 69%) than in European (23%) or South Asian (12%) ones — a reminder that allele frequency and disease frequency are different things. The measured effect is a small shift in the odds across a population of tens of thousands of people — not something that shows up in one person.
T/TNeither copy carries the associated allele at this position. SORCS3 is a brain-expressed sorting receptor involved in how neurons handle signalling proteins, and it turns up in genetic studies of several psychiatric traits rather than ADHD alone. On its own this says almost nothing about anyone: the effect of this position is a few percent, and ADHD involves thousands of positions plus a great deal that is not genetic.
ADHD is diagnosed by a clinician from behaviour observed in more than one setting, over time. No genotype contributes to that assessment, and nothing at this position rules the diagnosis in or out.
rs11591402 is a single position in the genome, in or near the SORCS3 gene. Published research associates it with adhd susceptibility (sorcs3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11591402 linked to?
On MyGeneLog this position is linked to ADHD (Attention Deficit Hyperactivity Disorder). The research behind each link, and its sources, are set out on that condition page.
Does having rs11591402 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11591402 come from?
Demontis et al., Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder, Nature Genetics 2019 (PMID 30478444) — meta-analysis of 20,183 diagnosed individuals and 35,191 controls. Position and alleles checked against Ensembl (GRCh38). Reported P = 4e-9. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 5432818222125Reads by AI crawlersClaude3ChatGPT2Google · Gemini8Perplexity1Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others25Total54Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.