Standard
Proinsulin levels
SLC30A8 · rs11558471
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Proinsulin levels compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Proinsulin levels.
G/G
Published research associates this genotype with typical/baseline likelihood of Proinsulin levels — no copies of the reported risk allele.
Source
Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
Strawbridge RJ,
Dupuis J,
Prokopenko I,
Barker A,
Ahlqvist E,
Rybin D,
Petrie JR,
Travers ME,
Bouatia-Naji N,
Dimas AS,
Nica A,
Wheeler E
and 91 more — show all
Chen H,
Voight BF,
Taneera J,
Kanoni S,
Peden JF,
Turrini F,
Gustafsson S,
Zabena C,
Almgren P,
Barker DJ,
Barnes D,
Dennison EM,
Eriksson JG,
Eriksson P,
Eury E,
Folkersen L,
Fox CS,
Frayling TM,
Goel A,
Gu HF,
Horikoshi M,
Isomaa B,
Jackson AU,
Jameson KA,
Kajantie E,
Kerr-Conte J,
Kuulasmaa T,
Kuusisto J,
Loos RJ,
Luan J,
Makrilakis K,
Manning AK,
Martínez-Larrad MT,
Narisu N,
Nastase Mannila M,
Ohrvik J,
Osmond C,
Pascoe L,
Payne F,
Sayer AA,
Sennblad B,
Silveira A,
Stancáková A,
Stirrups K,
Swift AJ,
Syvänen AC,
Tuomi T,
van 't Hooft FM,
Walker M,
Weedon MN,
Xie W,
Zethelius B,
Ongen H,
Mälarstig A,
Hopewell JC,
Saleheen D,
Chambers J,
Parish S,
Danesh J,
Kooner J,
Ostenson CG,
Lind L,
Cooper CC,
Serrano-Ríos M,
Ferrannini E,
Forsen TJ,
Clarke R,
Franzosi MG,
Seedorf U,
Watkins H,
Froguel P,
Johnson P,
Deloukas P,
Collins FS,
Laakso M,
Dermitzakis ET,
Boehnke M,
McCarthy MI,
Wareham NJ,
Groop L,
Pattou F,
Gloyn AL,
Dedoussis GV,
Lyssenko V,
Meigs JB,
Barroso I,
Watanabe RM,
Ingelsson E,
Langenberg C,
Hamsten A,
Florez JC
Diabetes · 2011 · PMID 21873549 · open access
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs11558471
What is rs11558471?
rs11558471 is a single position in the genome, in or near the SLC30A8 gene. Published research associates it with proinsulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What do people read about alongside rs11558471?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (13 papers), exercise and muscle (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs11558471 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11558471 come from?
GWAS Catalog, Diabetes 2011, PMID:21873549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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