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Who was studied 232 Hispanic or Latin American cases, 59,553 Hispanic or Latin American controls, 2,074 European ancestry cases, 448,199 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 2.17 lower (95% confidence interval 2.12-2.23); p = 4 × 10−11.
How common The C allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 4, band 4q21.21 — in an intron of LINC01088.
What each result means
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Meniere's disease (PheCode 386.1) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Meniere's disease (PheCode 386.1).
T/TPublished research associates this genotype with typical/baseline likelihood of Meniere's disease (PheCode 386.1) — no copies of the reported risk allele.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs115058055
What is rs115058055?
rs115058055 is a single position in the genome, in or near the LINC01088 gene. Published research associates it with meniere's disease (phecode 386.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs115058055 linked to?
On MyGeneLog this position is linked to Meniere's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs115058055 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs115058055 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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