Sensitive

Type 2 diabetes

near RNU6-1252P · rs114447556

Where this position leads

Condition: Type 2 Diabetes

rs114447556 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs114447556 rs114447556 near RNU6-12…

What the study found

Who was studied 148,726 European ancestry cases, 965,732 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0578 lower (95% confidence interval 0.04-0.075); p = 8 × 10−11.

How common The C allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 4, band 4q12 — between genes, 153.9 kb from RNU6-1252P.

What each result means

C/C Two copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/T No copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
Source

Questions about rs114447556

What is rs114447556?

rs114447556 is a single position in the genome, in or near the near RNU6-1252P gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs114447556 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs114447556 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114447556 come from?

GWAS Catalog, Nature genetics 2020, PMID:32541925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Type 2 diabetes (rs114447556). MyGeneLog™. https://www.mygenelog.com/variants/rs114447556

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