0 1922114Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others14Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 57,290 European ancestry cases, 324,430 European ancestry controls, 2,302 African American cases, 29,223 African American controls, 1,656 Hispanic or Latin American cases, 10,819 Hispanic or Latin American controls.
The effect
Each copy of the A allele shifted the measure 0.0996 higher (95% confidence interval 0.073-0.126); p = 1 × 10−13.
How common The A allele had a frequency of about 90% in the people studied.
Where it sits Chromosome 19, band 19p13.3 — in an intron of ABCA7.
What each result means
A/ATwo copies of the version the research linked to Age-related macular degeneration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Age-related macular degeneration. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Age-related macular degeneration. This is the starting point the study compared everyone against.
rs1137776 is a single position in the genome, in or near the ABCA7 gene. Published research associates it with age-related macular degeneration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1137776 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
Does having rs1137776 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1137776 come from?
GWAS Catalog, Nature genetics 2024, PMID:39623103. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1922114Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others14Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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