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Who was studied 7,402 European ancestry cases, 286,892 European ancestry controls; replicated in 134,700 European ancestry cases, 2,394,699 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−13.
Where it sits Chromosome 9, band 9p23 — in an intron of LURAP1L-AS1.
What each result means
A/ATwo copies of the version the research linked to Squamous cell carcinoma (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Squamous cell carcinoma (MTAG). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Squamous cell carcinoma (MTAG). This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36496446 · open access
Questions about rs1137134
What is rs1137134?
rs1137134 is a single position in the genome, in or near the LURAP1L-AS1 gene. Published research associates it with squamous cell carcinoma (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1137134 linked to?
On MyGeneLog this position is linked to Squamous Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs1137134 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1137134 come from?
GWAS Catalog, Nature communications 2022, PMID:36496446. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1814823Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI4Microsoft · Copilot8Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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