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Who was studied 218 European ancestry cases, 382 European ancestry controls.
The effect
Each copy of the T allele carried 2.71 times the odds of Diabetic neuropathy in type 2 diabetes (95% confidence interval 2.02-3.64); p = 3 × 10−11.
How common The T allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 4, band 4q31.21 — in the 3′ untranslated region of GUSBP5.
What each result means
C/CNo copy of the version the research linked to Diabetic neuropathy in type 2 diabetes. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Diabetic neuropathy in type 2 diabetes. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Diabetic neuropathy in type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
BMC medical genomics · 2021 · PMID 33430853 · open access
Questions about rs1132787
What is rs1132787?
rs1132787 is a single position in the genome, in or near the GYPA gene. Published research associates it with diabetic neuropathy in type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1132787 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs1132787 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1132787 come from?
GWAS Catalog, BMC medical genomics 2021, PMID:33430853. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 312Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others2Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Diabetic neuropathy in type 2 diabetes (rs1132787). MyGeneLog™. https://www.mygenelog.com/variants/rs1132787