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Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio

near LINC00524 · rs111878230

Where this position leads

Condition: Age-Related Macular Degeneration

rs111878230 Condition: Age-Related Macular Degeneration Age-Related Macular Degeneration Condition rs111878230 rs111878230 near LINC005…

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.207 higher (95% confidence interval 0.14-0.27); p = 3 × 10−10.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 14, band 14q32.31 — between genes, 13.2 kb from LINC00524.

What each result means

C/C No copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs111878230

What is rs111878230?

rs111878230 is a single position in the genome, in or near the near LINC00524 gene. Published research associates it with free cholesterol to cholesteryl esters in medium vldl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs111878230 linked to?

On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.

Does having rs111878230 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs111878230 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Free Cholesterol to Cholesteryl Esters in Medium VLDL ratio (rs111878230). MyGeneLog™. https://www.mygenelog.com/variants/rs111878230

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