TOMM40 · rs111784051
Where this position leads
Condition: Hypo-HDL-Cholesterolemia
What the study found
Who was studied 5,686 Korean ancestry cases, 45,122 Korean ancestry controls.
The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−50.
Where it sits Chromosome 19, band 19q13.32 — in an intron of TOMM40.
rs111784051 is a single position in the genome, in or near the TOMM40 gene. Published research associates it with hypercholesterolemia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Hypo-HDL-Cholesterolemia. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, International journal of molecular sciences 2022, PMID:36233190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hypercholesterolemia (rs111784051). MyGeneLog™. https://www.mygenelog.com/variants/rs111784051