C/CPublished research associates this genotype with typical/baseline likelihood of Intraocular pressure — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Intraocular pressure.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Intraocular pressure compared to the general population.
rs11147235 is a single position in the genome, in or near the ZNF140 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11147235 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs11147235 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11147235 come from?
GWAS Catalog, Hum Mol Genet 2018, PMID:29617998. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.