0 8125Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 30,309 African American or Afro-Caribbean cases, 84,722 African American or Afro-Caribbean controls, 8,523 Hispanic or Latin American cases, 48,779 Hispanic or Latin American controls, 1,127 East Asian ancestry cases, 5,402 East Asian ancestry controls, 56,207 European ancestry cases, 377,826 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.053 lower (95% confidence interval 0.039-0.067); p = 5 × 10−12.
How common The A allele had a frequency of about 79% in the people studied.
Where it sits Chromosome 12, band 12q23.3 — in an intron of SART3.
What each result means
A/ATwo copies of the version the research linked to Open-angle glaucoma (PheCode 365.1). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Open-angle glaucoma (PheCode 365.1). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Open-angle glaucoma (PheCode 365.1). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs11113989
What is rs11113989?
rs11113989 is a single position in the genome, in or near the SART3 gene. Published research associates it with open-angle glaucoma (phecode 365.1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11113989 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs11113989 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11113989 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 8125Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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