Standard

Hematological parameters

PTPN11 · rs11066301

Where this position leads

Condition: Blood Cell Counts

rs11066301 Condition: Blood Cell Counts Blood Cell Counts Condition rs11066301 rs11066301 PTPN11

What the study found

Who was studied 4,627 European ancestry individuals; replicated in 9,316 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 4.65 10^9/l higher (95% confidence interval 3.32-5.98); p = 8 × 10−12.

Where it sits Chromosome 12, band 12q24.13 — in an intron of PTPN11.

What each result means

A/A No copy of the version the research linked to Hematological parameters. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Hematological parameters. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Hematological parameters. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs11066301

What is rs11066301?

rs11066301 is a single position in the genome, in or near the PTPN11 gene. Published research associates it with hematological parameters. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11066301 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs11066301?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs11066301 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11066301 come from?

GWAS Catalog, Nat Genet 2009, PMID:19820697. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hematological parameters (rs11066301). MyGeneLog™. https://www.mygenelog.com/variants/rs11066301

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