Standard

Phospholipids to Total Lipids in Small HDL percentage

DNAH10 · rs11057393

Where this position leads

Condition: Age-Related Macular Degeneration

rs11057393 Condition: Age-Related Macular Degeneration Age-Related Macular Degeneration Condition rs11057393 rs11057393 DNAH10

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0259 higher (95% confidence interval 0.02-0.032); p = 1 × 10−18.

How common The T allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of DNAH10.

What each result means

C/C No copy of the version the research linked to Phospholipids to Total Lipids in Small HDL percentage. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Phospholipids to Total Lipids in Small HDL percentage. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Phospholipids to Total Lipids in Small HDL percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11057393

What is rs11057393?

rs11057393 is a single position in the genome, in or near the DNAH10 gene. Published research associates it with phospholipids to total lipids in small hdl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11057393 linked to?

On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.

Does having rs11057393 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11057393 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Phospholipids to Total Lipids in Small HDL percentage (rs11057393). MyGeneLog™. https://www.mygenelog.com/variants/rs11057393

← See all variants