2 33121723116Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others16Total33Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,311,438 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0158 higher (95% confidence interval 0.012-0.019); p = 5 × 10−19.
How common The C allele had a frequency of about 84% in the people studied.
Where it sits Chromosome 1, band 1p21.3 — in an intron of DPYD.
What each result means
C/CTwo copies of the version the research linked to Educational attainment (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Educational attainment (MTAG). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Educational attainment (MTAG). This is the starting point the study compared everyone against.
rs10875121 is a single position in the genome, in or near the DPYD gene. Published research associates it with educational attainment (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10875121 linked to?
On MyGeneLog this position is linked to Educational Attainment. The research behind each link, and its sources, are set out on that condition page.
Does rs10875121 affect how medicines work?
DPYD carries pharmacogenomic findings for Fluoropyrimidines. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.
Does having rs10875121 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10875121 come from?
GWAS Catalog, Nat Genet 2018, PMID:30038396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 33121723116Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others16Total33Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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