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Who was studied 380,506 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 7.14 z score lower; p = 9 × 10−13.
How common The T allele had a frequency of about 37% in the people studied.
Where it sits Chromosome 9, band 9p21.3 — in an intron of LINC03142.
What each result means
C/CNo copy of the version the research linked to Neurociticism. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Neurociticism. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Neurociticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2018 · PMID 29500382 · open access
Questions about rs10811883
What is rs10811883?
rs10811883 is a single position in the genome, in or near the ELAVL2 gene. Published research associates it with neurociticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10811883 linked to?
On MyGeneLog this position is linked to Irritable Mood. The research behind each link, and its sources, are set out on that condition page.
Does having rs10811883 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10811883 come from?
GWAS Catalog, Nature communications 2018, PMID:29500382. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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