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Who was studied 6,683 European ancestry cases, 12,173 European ancestry controls, 2,601 European ancestry affected sibling pair families, 69 European ancestry trios.
The effect
Each copy of the G allele carried 1.16 times the odds of Type 1 diabetes; p = 6 × 10−11.
How common The G allele had a frequency of about 41% in the people studied.
Where it sits Chromosome 10, band 10p15.1 — between genes, 4 kb from IL2RA.
What each result means
A/ANo copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2015 · PMID 25751624 · open access
Questions about rs10795791
What is rs10795791?
rs10795791 is a single position in the genome, in or near the IL2RA gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10795791 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs10795791 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10795791 come from?
GWAS Catalog, Nat Genet 2015, PMID:25751624. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 412227122122Reads by AI crawlersClaude2ChatGPT2Google · Gemini0Perplexity2Meta AI7Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others22Total41Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 1 diabetes (rs10795791). MyGeneLog™. https://www.mygenelog.com/variants/rs10795791