0 8125Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 38,064 African American or Afro-Caribbean cases, 76,856 African American or Afro-Caribbean controls, 11,570 Hispanic or Latin American cases, 45,339 Hispanic or Latin American controls, 1,446 East Asian ancestry cases, 5,057 East Asian ancestry controls, 81,303 European ancestry cases, 349,418 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0453 lower (95% confidence interval 0.035-0.055); p = 4 × 10−17.
How common The T allele had a frequency of about 58% in the people studied.
Where it sits Chromosome 11, band 11q23.3 — in an intron of ARHGEF12.
What each result means
C/CNo copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs10790382
What is rs10790382?
rs10790382 is a single position in the genome, in or near the ARHGEF12 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10790382 linked to?
On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs10790382 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10790382 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 8125Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others5Total8Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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