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Serum prostate-specific antigen levels

FGFR2 · rs10788160

What the study found

Who was studied 7,538 European ancestry individuals; replicated in 2,373 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 10.2 % higher; p = 5 × 10−15.

How common The A allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 10, band 10q26.12 — in an intron of LOC105378523.

What each result means

A/A Two copies of the version the research linked to Serum prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum prostate-specific antigen levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum prostate-specific antigen levels. This is the starting point the study compared everyone against.
Source

Questions about rs10788160

What is rs10788160?

rs10788160 is a single position in the genome, in or near the FGFR2 gene. Published research associates it with serum prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10788160 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10788160 come from?

GWAS Catalog, Sci Transl Med 2010, PMID:21160077. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum prostate-specific antigen levels (rs10788160). MyGeneLog™. https://www.mygenelog.com/variants/rs10788160

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