A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bipolar disorder compared to the general population. (GWAS Catalog, Am J Hum Genet 2011, PMID:21353194)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bipolar disorder. (GWAS Catalog, Am J Hum Genet 2011, PMID:21353194)
G/GPublished research associates this genotype with typical/baseline likelihood of Bipolar disorder — no copies of the reported risk allele. (GWAS Catalog, Am J Hum Genet 2011, PMID:21353194)
Source: GWAS Catalog, Am J Hum Genet 2011, PMID:21353194
Questions about rs1064395
What is rs1064395?
rs1064395 is a single position in the genome, in or near the NCAN gene. Published research associates it with bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1064395 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs1064395 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1064395 come from?
GWAS Catalog, Am J Hum Genet 2011, PMID:21353194. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.