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Who was studied 682 European ancestry cases, 1,300 European ancestry controls; replicated in 7,759 European ancestry cases, 34,062 European ancestry controls.
The effect
Each copy of the A allele carried 1.17 times the odds of Bipolar disorder; p = 2 × 10−9.
How common The A allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 19, band 19p13.11 — in the 3′ untranslated region of NCAN.
What each result means
A/ATwo copies of the version the research linked to Bipolar disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Bipolar disorder. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Bipolar disorder. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1064395
What is rs1064395?
rs1064395 is a single position in the genome, in or near the NCAN gene. Published research associates it with bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1064395 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs1064395?
Subjects that appear in the title or abstract of the same papers as this rsID include learning and focus (2 papers), brain and memory (2 papers), depression and stress (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1064395 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1064395 come from?
GWAS Catalog, Am J Hum Genet 2011, PMID:21353194. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 493254222227Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity5Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others27Total49Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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