C6orf57 · rs1048886
Where this position leads
Condition: Type 2 Diabetes
What the study found
Who was studied 2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls.
The effect Each copy of the G allele carried 1.54 times the odds of Type 2 diabetes (95% confidence interval 1.32-1.80); p = 3 × 10−8.
How common The G allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 6, band 6q13 — a missense change in SDHAF4.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs1048886 is a single position in the genome, in or near the C6orf57 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS Genet 2011, PMID:21490949. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes (rs1048886). MyGeneLog™. https://www.mygenelog.com/variants/rs1048886