2 514236222327Reads by AI crawlersClaude4ChatGPT2Google · Gemini0Perplexity3Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others27Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 218 European ancestry cases, 519 European ancestry controls; replicated in 1,153 European ancestry cases, 1,217 European ancestry controls.
The effect
Each copy of the T allele carried 2.80 times the odds of Psoriasis (95% confidence interval 2.40-3.30); p = 2 × 10−39.
How common The T allele had a frequency of about 15% in the people studied.
Where it sits Chromosome 6, band 6p21.33 — in an intron of LOC112267902.
What each result means
C/CNo copy of the version the research linked to Psoriasis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Psoriasis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs10484554
What is rs10484554?
rs10484554 is a single position in the genome, in or near the HLA-C gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10484554 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs10484554?
Subjects that appear in the title or abstract of the same papers as this rsID include gut and food intolerance (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs10484554 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10484554 come from?
GWAS Catalog, PLoS Genet 2008, PMID:18369459. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 514236222327Reads by AI crawlersClaude4ChatGPT2Google · Gemini0Perplexity3Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others27Total51Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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