0 2922624112Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity2Meta AI6Microsoft · Copilot0Amazon2Apple4China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 170,721 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0733 lower (95% confidence interval 0.065-0.082); p = 5 × 10−63.
How common The G allele had a frequency of about 21% in the people studied.
Where it sits Chromosome 19, band 19q13.42 — between genes, 0.2 kb from NLRP12.
What ClinVar records
ClassificationBenign; criteria provided, single submitter (1 of 4 stars, 1 submitter), last evaluated 2021-05-13.
ClinVar record 1275008NC_000019.10:g.53824615T>G
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
G/GTwo copies of the version the research linked to Monocyte count. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Monocyte count. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Monocyte count. This is the starting point the study compared everyone against.
rs10418046 is a single position in the genome, in or near the NLRP12 gene. Published research associates it with monocyte count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10418046 linked to?
On MyGeneLog this position is linked to Monocyte Count, Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs10418046 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10418046 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2922624112Reads by AI crawlersClaude0ChatGPT0Google · Gemini2Perplexity2Meta AI6Microsoft · Copilot0Amazon2Apple4China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total29Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.