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Bone properties (heel)

GPATCH1 · rs10416265

What the study found

Who was studied 2,483 East Asian ancestry individuals, 1,885 European ancestry individuals, 11,146 individuals; replicated in 10,074 European ancestry individuals, 2,870 European and other ancestry individuals, 21,434 individuals.

The effect Each copy of the G allele shifted the measure 0.06 higher (95% confidence interval 0.04-0.08); p = 4 × 10−12.

How common The G allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 19, band 19q13.11 — a missense change in GPATCH1.

What each result means

A/A No copy of the version the research linked to Bone properties (heel). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Bone properties (heel). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Bone properties (heel). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs10416265

What is rs10416265?

rs10416265 is a single position in the genome, in or near the GPATCH1 gene. Published research associates it with bone properties (heel). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs10416265?

Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs10416265 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10416265 come from?

GWAS Catalog, Hum Mol Genet 2014, PMID:24430505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Bone properties (heel) (rs10416265). MyGeneLog™. https://www.mygenelog.com/variants/rs10416265

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