Sensitive

Peyronie's disease (PheCode 604.3)

near WNT2 · rs10226248

Where this position leads

Condition: Peyronie's Disease

rs10226248 Condition: Peyronie's Disease Peyronie's Disease Condition rs10226248 rs10226248 near WNT2

What the study found

Who was studied 2,512 European ancestry cases, 413,591 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.422 higher (95% confidence interval 0.36-0.49); p = 1 × 10−37.

How common The G allele had a frequency of about 56% in the people studied.

Where it sits Chromosome 7, band 7q31.2 — between genes, 4.2 kb from WNT2.

What each result means

A/A No copy of the version the research linked to Peyronie's disease (PheCode 604.3). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Peyronie's disease (PheCode 604.3). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Peyronie's disease (PheCode 604.3). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10226248

What is rs10226248?

rs10226248 is a single position in the genome, in or near the near WNT2 gene. Published research associates it with peyronie's disease (phecode 604.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10226248 linked to?

On MyGeneLog this position is linked to Peyronie's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs10226248 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10226248 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Peyronie's disease (PheCode 604.3) (rs10226248). MyGeneLog™. https://www.mygenelog.com/variants/rs10226248

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