0 231123115Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 38,841 European ancestry cases, 451,248 European ancestry controls, 45,383 East Asian ancestry cases, 132,032 East Asian ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0511 lower (95% confidence interval 0.039-0.064); p = 2 × 10−15.
Where it sits Chromosome 7, band 7q36.3 — in an intron of UBE3C.
What each result means
C/CNo copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs1002389 is a single position in the genome, in or near the UBE3C gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1002389 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs1002389 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1002389 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 231123115Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others15Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes (rs1002389). MyGeneLog™. https://www.mygenelog.com/variants/rs1002389