RAP1A · rs494453
Where this position leads
Condition: Osteoporosis
Source: GWAS Catalog, PLoS Genet 2010, PMID:20548944
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs494453 is a single position in the genome, in or near the RAP1A gene. Published research associates it with osteoporosis-related phenotypes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Osteoporosis. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS Genet 2010, PMID:20548944. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.