Standard

QT interval

LIG3 · rs1052536

Where this position leads

Condition: QT Interval and Drug-Induced Long QT

rs1052536 Condition: QT Interval and Drug-Induced Long QT QT Interval and Drug-Induced Long QT Condition rs1052536 rs1052536 LIG3

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of QT interval compared to the general population. (GWAS Catalog, Nat Genet 2014, PMID:24952745)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with QT interval. (GWAS Catalog, Nat Genet 2014, PMID:24952745)
T/T Published research associates this genotype with typical/baseline likelihood of QT interval — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2014, PMID:24952745)

Source: GWAS Catalog, Nat Genet 2014, PMID:24952745

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs1052536

What is rs1052536?

rs1052536 is a single position in the genome, in or near the LIG3 gene. Published research associates it with qt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1052536 linked to?

On MyGeneLog this position is linked to QT Interval and Drug-Induced Long QT. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs1052536?

Subjects that appear in the title or abstract of the same papers as this rsID include allergies (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs1052536 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1052536 come from?

GWAS Catalog, Nat Genet 2014, PMID:24952745. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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