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Who was studied 426,824 British ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.013 higher (95% confidence interval 0.0092-0.0169); p = 4 × 10−11.
How common The C allele had a frequency of about 56% in the people studied.
Where it sits Chromosome 21, band 21q22.12 — in a regulatory region of RUNX1.
What each result means
C/CTwo copies of the version the research linked to Heel bone mineral density. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Heel bone mineral density. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Heel bone mineral density. This is the starting point the study compared everyone against.
Nature genetics · 2019 · PMID 30598549 · open access
Questions about rs9984655
What is rs9984655?
rs9984655 is a single position in the genome, in or near the LOC100506403 gene. Published research associates it with heel bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9984655 linked to?
On MyGeneLog this position is linked to Heel Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.
Does having rs9984655 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9984655 come from?
GWAS Catalog, Nature genetics 2019, PMID:30598549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Heel bone mineral density (rs9984655). MyGeneLog™. https://www.mygenelog.com/variants/rs9984655