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Atrial fibrillation (MTAG)

RUNX1 · rs9981470

Where this position leads

Condition: Atrial Fibrillation

rs9981470 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs9981470 rs9981470 RUNX1

What the study found

Who was studied 296,021 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 5.5 z-score higher; p = 4 × 10−8.

How common The T allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 21, band 21q22.12 — inside RUNX1.

What each result means

C/C No copy of the version the research linked to Atrial fibrillation (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Atrial fibrillation (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Atrial fibrillation (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9981470

What is rs9981470?

rs9981470 is a single position in the genome, in or near the RUNX1 gene. Published research associates it with atrial fibrillation (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9981470 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs9981470 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9981470 come from?

GWAS Catalog, NPJ genomic medicine 2025, PMID:41022758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (MTAG) (rs9981470). MyGeneLog™. https://www.mygenelog.com/variants/rs9981470

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