Standard

Waist-hip ratio

DSCR4 · rs9976841

Where this position leads

Condition: Waist-to-Hip Ratio (Body Fat Distribution)

rs9976841 Condition: Waist-to-Hip Ratio (Body Fat Distribution) Waist-to-Hip Ratio (Body Fat Distri… Condition rs9976841 rs9976841 DSCR4

What the study found

Who was studied 697,734 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0129 lower (95% confidence interval 0.0094-0.0164); p = 2 × 10−12.

How common The A allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 21, band 21q22.13 — in an intron of DSCR4.

What each result means

A/A Two copies of the version the research linked to Waist-hip ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Waist-hip ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Waist-hip ratio. This is the starting point the study compared everyone against.
Source

Questions about rs9976841

What is rs9976841?

rs9976841 is a single position in the genome, in or near the DSCR4 gene. Published research associates it with waist-hip ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9976841 linked to?

On MyGeneLog this position is linked to Waist-to-Hip Ratio (Body Fat Distribution). The research behind each link, and its sources, are set out on that condition page.

Does having rs9976841 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9976841 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Waist-hip ratio (rs9976841). MyGeneLog™. https://www.mygenelog.com/variants/rs9976841

← See all variants