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Plasma thyroid-stimulating hormone levels

NR3C2 · rs9968300

What the study found

Who was studied 1,680 Danish ancestry children and adolescents; replicated in 2,129 Danish ancestry children and adolescents.

The effect Each copy of the C allele shifted the measure 0.194 higher (95% confidence interval 0.14-0.25); p = 2 × 10−11.

How common The C allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 4, band 4q31.23 — in an intron of LOC107986195.

What each result means

A/A No copy of the version the research linked to Plasma thyroid-stimulating hormone levels. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Plasma thyroid-stimulating hormone levels. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Plasma thyroid-stimulating hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9968300

What is rs9968300?

rs9968300 is a single position in the genome, in or near the NR3C2 gene. Published research associates it with plasma thyroid-stimulating hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9968300 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9968300 come from?

GWAS Catalog, PLoS One 2017, PMID:28333968. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Plasma thyroid-stimulating hormone levels (rs9968300). MyGeneLog™. https://www.mygenelog.com/variants/rs9968300

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