0 7124Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 228,926 European ancestry cases, 1,611,415 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.0932 lower (95% confidence interval 0.068-0.118); p = 4 × 10−13.
How common The C allele had a frequency of about 98% in the people studied.
Where it sits Chromosome 18, band 18q23 — in an intron of ZNF516.
What each result means
C/CTwo copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40645996 · open access
Questions about rs9954310
What is rs9954310?
rs9954310 is a single position in the genome, in or near the ZNF516 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs9954310 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs9954310 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs9954310 come from?
GWAS Catalog, Nature communications 2025, PMID:40645996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 7124Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total7Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.