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Obesity (extreme)

FTO · rs9941349

Where this position leads

Conditions: Obesity and Body Weight, Osteoarthritis

rs9941349 Condition: Obesity and Body Weight Obesity and Body Weight Condition Condition: Osteoarthritis Osteoarthritis Condition rs9941349 rs9941349 FTO

What the study found

Who was studied 775 European ancestry cases, 3,197 European ancestry controls.

The effect Each copy of the T allele carried 1.48 times the odds of Obesity (extreme) (95% confidence interval 1.33-1.66); p = 6 × 10−12.

How common The T allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 16, band 16q12.2 — in an intron of FTO.

What each result means

C/C No copy of the version the research linked to Obesity (extreme). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Obesity (extreme). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Obesity (extreme). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs9941349

What is rs9941349?

rs9941349 is a single position in the genome, in or near the FTO gene. Published research associates it with obesity (extreme). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9941349 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight, Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs9941349?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers), sleep and insomnia (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs9941349 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9941349 come from?

GWAS Catalog, Hum Mol Genet 2009, PMID:19553259. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Obesity (extreme) (rs9941349). MyGeneLog™. https://www.mygenelog.com/variants/rs9941349

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