Standard
Atopic march
SLC6A15 · rs993226
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Atopic march compared to the general population.
G/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Atopic march.
T/T
Published research associates this genotype with typical/baseline likelihood of Atopic march — no copies of the reported risk allele.
Source
Meta-analysis identifies seven susceptibility loci involved in the atopic march
Marenholz I,
Esparza-Gordillo J,
Rüschendorf F,
Bauerfeind A,
Strachan DP,
Spycher BD,
Baurecht H,
Margaritte-Jeannin P,
Sääf A,
Kerkhof M,
Ege M,
Baltic S
and 61 more — show all
Matheson MC,
Li J,
Michel S,
Ang WQ,
McArdle W,
Arnold A,
Homuth G,
Demenais F,
Bouzigon E,
Söderhäll C,
Pershagen G,
de Jongste JC,
Postma DS,
Braun-Fahrländer C,
Horak E,
Ogorodova LM,
Puzyrev VP,
Bragina EY,
Hudson TJ,
Morin C,
Duffy DL,
Marks GB,
Robertson CF,
Montgomery GW,
Musk B,
Thompson PJ,
Martin NG,
James A,
Sleiman P,
Toskala E,
Rodriguez E,
Fölster-Holst R,
Franke A,
Lieb W,
Gieger C,
Heinzmann A,
Rietschel E,
Keil T,
Cichon S,
Nöthen MM,
Pennell CE,
Sly PD,
Schmidt CO,
Matanovic A,
Schneider V,
Heinig M,
Hübner N,
Holt PG,
Lau S,
Kabesch M,
Weidinger S,
Hakonarson H,
Ferreira MAR,
Laprise C,
Freidin MB,
Genuneit J,
Koppelman GH,
Melén E,
Dizier MH,
Henderson AJ,
Lee YA
Nature communications · 2015 · PMID 26542096 · open access
Questions about rs993226
What is rs993226?
rs993226 is a single position in the genome, in or near the SLC6A15 gene. Published research associates it with atopic march. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs993226 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs993226 come from?
GWAS Catalog, Nat Commun 2015, PMID:26542096. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants