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Obesity-related traits

FTO · rs9930506

Where this position leads

Condition: Obesity and Body Weight

rs9930506 Condition: Obesity and Body Weight Obesity and Body Weight Condition Topic: Blood sugar and insulin Blood sugar and insulin Topic Topic: Cholesterol and blood fats Cholesterol and blood fats Topic Topic: Exercise and muscle Exercise and muscle Topic rs9930506 rs9930506 FTO

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 4,741 Sardinian individuals; replicated in 3,205 African American, Hispanic, and European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.12 SD lower; p = 9 × 10−7.

How common The A allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 16, band 16q12.2 — in an intron of FTO.

What each result means

A/A Two copies of the version the research linked to Obesity-related traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Obesity-related traits. That is a smaller link than two copies.
G/G No copy of the version the research linked to Obesity-related traits. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs9930506

What is rs9930506?

rs9930506 is a single position in the genome, in or near the FTO gene. Published research associates it with obesity-related traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9930506 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs9930506?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (6 papers), exercise and muscle (4 papers), cholesterol and blood fats (4 papers), bones and fractures (4 papers), kidneys (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs9930506 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9930506 come from?

GWAS Catalog, PLoS Genet 2007, PMID:17658951. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Obesity-related traits (rs9930506). MyGeneLog™. https://www.mygenelog.com/variants/rs9930506

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