Sensitive

Alcohol use disorder

FTO · rs9926289

Where this position leads

Condition: Alcohol Use Disorder

rs9926289 Condition: Alcohol Use Disorder Alcohol Use Disorder Condition rs9926289 rs9926289 FTO

What the study found

Who was studied 57,564 European ancestry cases, 256,395 European ancestry controls.

The effect Each copy of the A allele shifted the measure 7.17 lower; p = 7 × 10−13.

How common The A allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 16, band 16q12.2 — in an intron of FTO.

What each result means

A/A Two copies of the version the research linked to Alcohol use disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Alcohol use disorder. That is a smaller link than two copies.
G/G No copy of the version the research linked to Alcohol use disorder. This is the starting point the study compared everyone against.
Source

Questions about rs9926289

What is rs9926289?

rs9926289 is a single position in the genome, in or near the FTO gene. Published research associates it with alcohol use disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9926289 linked to?

On MyGeneLog this position is linked to Alcohol Use Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs9926289 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9926289 come from?

GWAS Catalog, Nature neuroscience 2020, PMID:32451486. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alcohol use disorder (rs9926289). MyGeneLog™. https://www.mygenelog.com/variants/rs9926289

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