Sensitive

Breast cancer anti-estrogen resistance protein 3 levels

KRT18P55 · rs9901901

Where this position leads

Condition: Breast Cancer

rs9901901 Condition: Breast Cancer Breast Cancer Condition rs9901901 rs9901901 KRT18P55

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.32 higher (95% confidence interval 0.24-0.4); p = 1 × 10−13.

Where it sits Chromosome 17, band 17q11.2 — in an intron of KRT18P55.

What each result means

C/C Two copies of the version the research linked to Breast cancer anti-estrogen resistance protein 3 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Breast cancer anti-estrogen resistance protein 3 levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Breast cancer anti-estrogen resistance protein 3 levels. This is the starting point the study compared everyone against.
Source

Questions about rs9901901

What is rs9901901?

rs9901901 is a single position in the genome, in or near the KRT18P55 gene. Published research associates it with breast cancer anti-estrogen resistance protein 3 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9901901 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs9901901 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9901901 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Breast cancer anti-estrogen resistance protein 3 levels (rs9901901). MyGeneLog™. https://www.mygenelog.com/variants/rs9901901

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