Sensitive

Stroke

CHD3 · rs9899375

Where this position leads

Condition: Ischaemic Stroke

rs9899375 Condition: Ischaemic Stroke Ischaemic Stroke Condition rs9899375 rs9899375 CHD3

What the study found

Who was studied up to 1,592 African American cases, up to 13,154 African American controls.

The effect Each copy of the T allele carried 2.57 times the odds of Stroke (95% confidence interval 1.86-3.55); p = 1 × 10−8.

How common The T allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 17, band 17p13.1 — in an intron of CHD3.

What each result means

C/C No copy of the version the research linked to Stroke. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Stroke. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Stroke. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs9899375

What is rs9899375?

rs9899375 is a single position in the genome, in or near the CHD3 gene. Published research associates it with stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9899375 linked to?

On MyGeneLog this position is linked to Ischaemic Stroke. The research behind each link, and its sources, are set out on that condition page.

Does having rs9899375 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9899375 come from?

GWAS Catalog, Stroke 2015, PMID:26089329. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Stroke (rs9899375). MyGeneLog™. https://www.mygenelog.com/variants/rs9899375

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