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Insomnia

HEXIM1 · rs9894577

Where this position leads

Conditions: Insomnia, Osteoarthritis

rs9894577 Condition: Insomnia Insomnia Condition Condition: Osteoarthritis Osteoarthritis Condition rs9894577 rs9894577 HEXIM1

What the study found

Who was studied 404,588 European ancestry individuals, 17,651 European, Hispanic and African ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−10.

How common The A allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 17, band 17q21.31 — between genes, 1.7 kb from ACBD4.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insomnia compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insomnia.
G/G Published research associates this genotype with typical/baseline likelihood of Insomnia — no copies of the reported risk allele.
Source

Questions about rs9894577

What is rs9894577?

rs9894577 is a single position in the genome, in or near the HEXIM1 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs9894577 linked to?

On MyGeneLog this position is linked to Insomnia, Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs9894577 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9894577 come from?

GWAS Catalog, Scientific reports 2020, PMID:32332799. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs9894577). MyGeneLog™. https://www.mygenelog.com/variants/rs9894577

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