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Concentration of large VLDL particles

PEMT · rs9889584

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0536 lower (95% confidence interval 0.037-0.07); p = 8 × 10−11.

How common The G allele had a frequency of about 94% in the people studied.

Where it sits Chromosome 17, band 17p11.2 — in an intron of PEMT.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Concentration of large VLDL particles — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Concentration of large VLDL particles.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Concentration of large VLDL particles compared to the general population.
Source

Questions about rs9889584

What is rs9889584?

rs9889584 is a single position in the genome, in or near the PEMT gene. Published research associates it with concentration of large vldl particles. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9889584 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9889584 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Concentration of large VLDL particles (rs9889584). MyGeneLog™. https://www.mygenelog.com/variants/rs9889584

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