Standard
Hypospadias
PKDCC · rs988958
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Hypospadias — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2014, PMID:25108383)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hypospadias. (GWAS Catalog, Nat Genet 2014, PMID:25108383)
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hypospadias compared to the general population. (GWAS Catalog, Nat Genet 2014, PMID:25108383)
Source
Genome-wide association analyses identify variants in developmental genes associated with hypospadias
Geller F,
Feenstra B,
Carstensen L,
Pers TH,
van Rooij IA,
Körberg IB,
Choudhry S,
Karjalainen JM,
Schnack TH,
Hollegaard MV,
Feitz WF,
Roeleveld N
and 7 more — show all
Nature genetics · 2014 · PMID 25108383
Questions about rs988958
What is rs988958?
rs988958 is a single position in the genome, in or near the PKDCC gene. Published research associates it with hypospadias. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs988958 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs988958 come from?
GWAS Catalog, Nat Genet 2014, PMID:25108383. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants